Eukaryotic elongation factor-2 kinase
WebPhosphorylation of the mRNA translational factor eukaryotic elongation factor 2 (eEF2) by its specific kinase eEF2K is critically involved in protein synthesis regulation. In this … WebJan 23, 2007 · Protein Elongation factor 2 Gene EEF2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 858 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Add a publication Entry feedback Function
Eukaryotic elongation factor-2 kinase
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WebJul 12, 2015 · EEF2K (eukaryotic elongation factor-2 kinase), also known as Ca2+/calmodulin-dependent protein kinase III, functions in downregulating peptide chain … WebOct 24, 2024 · Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) acts to inhibit protein translation through phosphorylating a specific substrate, eEF2. We previously found that the increased eEF2K expression in mesenteric artery mediates hypertension development in spontaneously hypertensive rats.
Webtion throughout essentially all eukaryotic species. The elongation step of translation is also subject to regula-tion by phosphorylation in eukaryotes. For example, eukary-otic elongation factor 1A (eEF1A) can be phosphorylated on threonine 431 by protein kinase C in mammalian cells (26). Insulin can also increase the phosphorylation of eEF1A, as WebAngiogenesis is crucial for tumor formation, development and metastasis in HCC. Previous studies indicated that high expression levels of elongation factor 2 kinase (eEF2K), a …
WebDec 15, 2024 · Maintenance of memory and synaptic plasticity relies on de novo protein synthesis, which is partially regulated by phosphorylation of …
WebNov 27, 2024 · Eukaryotic elongation factor 2 kinase (eEF2K) is a highly unusual protein kinase that negatively regulates the elongation step of protein synthesis.
WebAbstract. Eukaryotic elongation factor-2 kinase (eEF2K), an atypical member of alpha-kinase family, is highly overexpressed in breast, pancreatic, brain, and lung cancers, … make the font smallerWebProtein synthesis is highly regulated via both initiation and elongation. One mechanism that inhibits elongation is phosphorylation of eukaryotic elongation factor 2 (eEF2) on … make the fox rushWebJul 8, 2024 · Eukaryotic elongation factor 2 kinase (eEF2K), a member of the atypical protein kinase family of alpha-kinases, is well-known as a negative regulator of protein … make the footer stick to the bottom of a pageWebFinally, we show that oxLDL, by activating eEF2 kinase, phosphorylates and therefore inhibits eEF2, resulting in an overall decrease in protein synthesis. Conclusion— These results indicate a novel signaling pathway in which oxLDL can block macrophage apoptosis by mobilizing calcium and activating eEF2 kinase. … make the frickin frogs gay remixWebAug 31, 2024 · Eukaryotic Elongation Factor-2 kinase (EF2K) acts as a negative regulator of protein synthesis, translation, and cell growth. As a structurally unique member of … make the game more fun szironcat.comWebMay 20, 2024 · Background: Eukaryotic elongation factor 2 kinase (eEF2K) regulates the elongation stage of protein synthesis by phosphorylating eEF2, a process related to various diseases including cancer and cardiovascular and neurodegenerative diseases. make the forest part of your storyWebEukaryotic elongation factor 2 kinase (eEF2K) is an atypical protein kinase that controls protein synthesis in cells under stress. Although well studied in cancer, less is known … make the future fm nack5